A transcription factor collective defines cardiac cell fate and reflects lineage history

Junion G*, Spivakov M*, Girardot C, Braun M, Gustafson EH, Birney E, Furlong EE
* These authors contributed equally to this work.
Cell, 148(3):473-486.
Read it on: Europe PMC | DOI: 10.1016/j.cell.2012.01.030

Data

All coordinates are relative to the dm3 assembly.

We provide the ChIP-chip signal, i.e. log2(IP/Mock) and smoothed with a bandwidth of 5 probes, for each transcription factor and developmental time used in this study. The signal is provided as bigwig files (14 files ~550Mb):

The Tinman and Biniou datasets are from Zinzen et al., 2009 – reprocessed with dm3.

ChIP-chip signal files

We also provide the regions of strong ChIP enrichment for the five cardiogenic transcription factors (Suppl. Table 1) as reported by TileMap as well as Cis-Regulatory Modules (CRMs) defined by the binding of cardiogenic transcription factors (Suppl. Table 2):

Suppl. Table 1: TileMap Regions of strong ChIP enrichment for the five cardiogenic transcription factors
Suppl. Table 2: CRMs defined by the binding of cardiogenic transcription factors

Raw data is available at ArrayExpress:

Accession E-TABM-1184