Chip (Ldb1) is a putative cofactor of Zelda forming a functional bridge to CBP during zygotic genome activation

We provide the spike-in CUT&Tag bigwigs, spike-in ATAC-seq bigwigs, ChIP-seq bigwigs, RNA-seq gene expression tables, Capture-C interactions and Hi-C contact matrices.

spike-in CUT&Tag bigwig tracks:

• Chip-iLEXY line – Dark – Chip Antibody
• Chip-iLEXY line – Blue Light – Chip Antibody
• Chip-iLEXY line – Dark – Zelda Antibody
• Chip-iLEXY line – Blue Light – Zelda Antibody
• Chip-iLEXY line – Dark – CBP Antibody
• Chip-iLEXY line – Blue Light – CBP Antibody
• Chip-iLEXY line – Dark – BRD4 Antibody
• Chip-iLEXY line – Blue Light – BRD4 Antibody
• Chip-iLEXY line – Dark – H3K27ac Antibody
• Chip-iLEXY line – Blue Light – H3K27ac Antibody
• Chip-iLEXY line – Dark – H4K8ac Antibody
• Chip-iLEXY line – Blue Light – H4K8ac Antibody
• Chip-iLEXY line – Dark – H3K27ac Antibody
• Chip-iLEXY line – Blue Light – H3K27ac Antibody
• Chip-iLEXY line 6-8h – Dark – Chip Antibody
• Chip-iLEXY line 6-8h – Blue Light – Chip Antibody
• Chip-iLEXY line 10-12h – Dark – Chip Antibody
• Chip-iLEXY line 10-12h – Blue Light – Chip Antibody
• yellow white line – Chip Antibody
• ZeldaKO line – Chip Antibody
• yellow white line – Zelda Antibody
• ZeldaKO line – Zelda Antibody

spike-in ATAC-seq bigwig tracks:

• Chip-iLEXY line – Dark
• Chip-iLEXY line – Blue Light
• yellow white line
• ZeldaKO line

ChIP-seq bigwig tracks:

• ChIP-seq Chip Antibody NC14 rep1
• ChIP-seq Chip Antibody NC14 rep2
• ChIP-seq Chip Antibody 2-4h rep1
• ChIP-seq Chip Antibody 2-4h rep2
• ChIP-seq Chip Antibody 6-8h rep1
• ChIP-seq Chip Antibody 6-8h rep2
• ChIP-seq Chip Antibody 10-12h rep1
• ChIP-seq Chip Antibody 10-12h rep2

RNA-seq expression counts and differential expression (DESeq2):

• Chip-iLEXY Dark and BlueLight 2-3h expression counts
• Chip-iLEXY Dark and BlueLight 2-4h expression counts
• Chip-iLEXY Dark and BlueLight 6-7h expression counts
• Chip-iLEXY Dark and BlueLight 10-12h expression counts
• Chip-iLEXY Dark and BlueLight 2-3h DESeq
• Chip-iLEXY Dark and BlueLight 2-4h DESeq
• Chip-iLEXY Dark and BlueLight 6-7h DESeq
• Chip-iLEXY Dark and BlueLight 10-12h DESeq

Capture-C interactions, oligos and .bedpe:

• reference dm6 genome DpnII digest
• oligo_info.txt
• Capture-C all interactions
• Capture-C bedpe Chip-iLEXY Dark rep1
• Capture-C bedpe Chip-iLEXY Dark rep2
• Capture-C bedpe Chip-iLEXY Blue Light rep1
• Capture-C bedpe Chip-iLEXY Blue Light rep2

Hi-C contact matrices:

• Hi-C contact matrix 10kb Dark
• Hi-C contact matrix 10kb Blue Light

You can find the raw data files on European Nucleotide Archive:

• PRJEB88444 – spike-in CUT&Tag
• PRJEB88395 – spike-in ATAC-seq
• PRJEB88447 – Chip-Seq
• PRJEB88442 – RNA-Seq
• PRJEB88446 – Capture-C
• PRJEB88443 – Hi-C