- Elected Academia Europaea Member 2016
- Elected EMBO Member since 2013
- ERC Advanced Investigator since 2013
- Head of Genome Biology Unit (EMBL) since 2009
- Senior Scientist (EMBL) since 2009
- Group leader at EMBL since September 2002
- Postdoctoral research at Stanford University (1997-2002)
- Ph.D., University College Dublin (1996)
Charles is also the head of the Genome Biology Computational Support at EMBL. Check out their website: gbcs.embl.de
Alek is a computational biologist. His personal website: www.mimuw.edu.pl/~ajank/
Collaborators & Associated Colleagues
Alumniand their current positions
Former Post-doctoral Fellows
(Feb. 2016) Hummingbird Diagnostics GmbH Heidelberg, Germany
The prime focus of the Institute of Medical Systems Biology, located in the Center for Molecular Neurobiology in Hamburg (ZMNH), is to understand human pathology, especially in the central nervous system. To this end, ‘big’ biomedical data are integrated and curated using automated systems and disease-relevant information is extracted using statistical and machine learning approaches. The gained insights are then used to understand, predict, and potentially cure human malady.
David is an evolutionary biologist. He now has his own lab in Berlin. Check out his research www.garfieldlab.org/
ENS of Lyon Lyon, France
Yad’s group uses Drosophila embryogenesis as a model system to provide a unique view of the functionality of enhancer-promoter interactions in a developing embryo. She applies an interdisciplinary approach that combines genetics, genomics, and computational biology.
(Nov. 2012) Development & Reproduction Genetics (GReD), INSERM U1103, CNRS UMR6293
University of Clermont-Ferrand Clermont-Ferrand, France
Guillaume now works on the diversification of muscle and heart cells in development and in pathological conditions. He studies the process of cell diversification via transcriptional and post-transcriptional regulation, with the help of targeted transcriptomic approaches and specific gene disruption. The goal is to identify molecular mechanisms giving rise to particular muscle or cardiac cells types.
Pierre and his group’s main focus is to understand principles of transcriptional regulation in development and cancer. They combine computational and experimental approaches to contrast information between healthy and disease states in order to understand mechanisms impacting gene regulation and expression in diseases.
The Saunders lab is increasing the understanding of temporal and spatial regulation of patterning and growth during development. They are currently (2016) focusing on:
- How embryos regulate time during development
- How the embryo ensures robust cell migration
- How topologically complex organs form and scale in the embryo
Molecular Biology and Neuroscience Buenos-Aires, Argentina
Ignacio is interested in the regulation of gene expression from an integrative point of view. In particular, how transcriptional and post-transcriptional mechanisms interact with each other to define expression patterns, and how this process is affected by contextual elements such as chromatin structure and non-coding RNA expression.
Bartek is interested in computational biology approaches to decipher gene expression regulation mechanisms. His lab focuses mainly on the role of chromatin state in transcription regulation (building probabilistic models relating transcription factor binding, histone modifications and chromatin interactions with the transcriptional events occuring in developing organisms) and on modeling gene regulatory networks (computational approaches to network reconstruction).
Robert’s lab also uses the fruit fly Drosophila melanogaster as a model to understand how cells become different – how do their gene expression programs change over the course of development, and how does this guide and allow for cellular specification and differentiation, focusing on nervous system development.