Browse data

The 4C Browser runs with our in-house Dynamix plugin, for automated genome browsing. Learn more about it here.

The Furlong lab maintains and serves an instance of a genome browser (JBrowse) where our 4C data is made available for browsing. Click on the browser thumbnail to access to the 4C Browser.

Download data

Our publication page allows you to access the data associated with our publications. Links are also gathered below

Promoter shape varies across populations and impacts promoter evolution and expression noise.

Schor IE, Degner JF, Harnett D, Cannavo E, Casale FP, Shim H, Garfield D, Birney E, Stephens M, Stegle O, Furlong EE (2017)

Nature Genetics 2017 Feb 13. doi: 10.1038/ng.3791 | Europe PMC | doi

Co-corresponding authors

Genetic variants regulating expression levels and isoform diversity during embryogenesis

Cannavò E*, Koelling N*, Harnett D, Garfield D, Casale FP, Ciglar L, Gustafson HE, Viales RR, Marco-Ferreres R, Degner JF, Zhao B, Stegle O, Birney E, Furlong EE (2016)

Nature 541(7637):402-406. doi: 10.1038/nature20802 | Europe PMC | doi

* These authors contributed equally to this work.

Co-corresponding authors

Identification and in silico modeling of enhancers reveals new features of the cardiac differentiation network

Seyres D, Ghavi-Helm Y*, Junion G*, Taghli-Lamallem O, Guichard C, Röder L, Girardot C, Furlong EE and Perrin L (2016)

Development 143(23):4533-4542. doi: 10.1242/dev.140822 | Europe PMC | doi

* These authors contributed equally to this work.

Co-corresponding authors

Enhancer loops appear stable during development and are associated with paused polymerase

Ghavi-Helm Y, Klein FA, Pakozdi T, Ciglar L, Noordermeer D, Huber W, Furlong EE (2014)

Nature 512(7512):96-100. doi: 10.1038/nature13417 | Europe PMC | doi

Coordinated repression and activation of two transcriptional programs stabilizes cell fate during myogenesis

Ciglar L, Girardot C, Wilczyński B, Braun M, Furlong EE (2014)

Development 141:2633-2643. doi: 10.1242/dev.101956 | Europe PMC | doi

A conserved role for Snail as a potentiator of active transcription

Rembold M*, Ciglar L*, Yáñez-Cuna JO, Zinzen RP, Girardot C, Jain A, Welte MA, Stark A, Leptin M, Furlong EE (2014)

Genes Dev. 28:167-181. doi: 10.1101/gad.230953.113 | Europe PMC | doi

* These authors contributed equally to this work.

Co-corresponding authors

Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development

Bonn S*, Zinzen RP*, Girardot C*, Gustafson EH, Perez-Gonzalez A, Delhomme N, Ghavi-Helm Y, Wilczyński B, Riddell A, Furlong EE (2012)

Nat. Genet. 44(2):148-156. doi: 10.1038/ng.1064 | Europe PMC | doi

* These authors contributed equally to this work.

A transcription factor collective defines cardiac cell fate and reflects lineage history

Junion G*, Spivakov M*, Girardot C, Braun M, Gustafson EH, Birney E, Furlong EE (2012)

Cell 148(3):473-486. doi: 10.1016/j.cell.2012.01.030 | Europe PMC | doi

* These authors contributed equally to this work.

Combinatorial binding leads to diverse regulatory responses: Lmd is a tissue-specific modulator of Mef2 activity

Cunha PM*, Sandmann T*, Gustafson EH, Ciglar L, Eichenlaub MP, Furlong EE (2010)

PLoS Genet. 6(7):e1001014. doi: 10.1371/journal.pgen.1001014 | Europe PMC | doi

* These authors contributed equally to this work.

Dynamic CRM occupancy reflects a temporal map of developmental progression

Wilczyński B, Furlong EE (2010)

Mol. Syst. Biol. 6:383. doi: 10.1038/msb.2010.35 | Europe PMC | doi

Combinatorial binding predicts spatio-temporal cis-regulatory activity

Zinzen RP*, Girardot C*, Gagneur J*, Braun M, Furlong EE (2009)

Nature 462(7269):65-70. doi: 10.1038/nature08531 | Europe PMC | doi

* These authors contributed equally to this work.

A systematic analysis of Tinman function reveals Eya and JAK-STAT signaling as essential regulators of muscle development

Liu YH, Jakobsen JS, Valentin G, Amarantos I, Gilmour DT, Furlong EE (2009)

Temporal ChIP-on-chip reveals Biniou as a universal regulator of the visceral muscle transcriptional network

Jakobsen JS, Braun M, Astorga J, Gustafson EH, Sandmann T, Karzynski M, Carlsson P, Furlong EE (2007)

Genes Dev. 21(19):2448-2460. doi: 10.1101/gad.437607 | Europe PMC | doi

A core transcriptional network for early mesoderm development in Drosophila melanogaster

Sandmann T, Girardot C, Brehme M, Tongprasit W, Stolc V, Furlong EE (2007)

Genes Dev. 21(4):436-449. doi: 10.1101/gad.1509007 | Europe PMC | doi

A temporal map of transcription factor activity: mef2 directly regulates target genes at all stages of muscle development

Sandmann T, Jensen LJ, Jakobsen JS, Karzynski MM, Eichenlaub MP, Bork P, Furlong EE (2006)

Dev. Cell 10(6):797-807. doi: 10.1016/j.devcel.2006.04.009 | Europe PMC | doi